Hip Fracture and Proton Pump Inhibitor Therapy: Position Statement
نویسندگان
چکیده
منابع مشابه
Long-term proton pump inhibitor therapy and risk of hip fracture.
CONTEXT Proton pump inhibitors (PPIs) may interfere with calcium absorption through induction of hypochlorhydria but they also may reduce bone resorption through inhibition of osteoclastic vacuolar proton pumps. OBJECTIVE To determine the association between PPI therapy and risk of hip fracture. DESIGN, SETTING, AND PATIENTS A nested case-control study was conducted using the General Practi...
متن کاملProton pump inhibitors therapy and risk of hip fracture: a systematic review and meta-analysis.
BACKGROUND AND AIMS Previous studies have reported inconsistent findings that proton pump inhibitors (PPIs) therapy might increase the risk of hip fracture. We investigated the association between PPIs therapy and hip fracture by a systematic review and meta-analysis. METHODS We systematically searched PubMed, EMBASE, and the Cochrane Library. We included studies assessing the effects of PPIs...
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S hould Helicobacter pylori infection be eradicated in patients requiring maintenance proton pump inhibitor therapy for gastro-oesophageal reflux disease? This question has stimulated heated debate and contention over the past few years. The issue first came to prominence in 1996 when Kuipers et al published their study purporting to demonstrate that omeprazole accelerated the development of co...
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The aim of this study was to compare the efficacy and tolerability of the first-line Helicobacter pylori (H. pylori) eradication regimen composed of proton pump inhibitor, clarithromycin, and amoxicillin, with those of a regimen composed of proton pump inhibitor, metronidazole, and amoxicillin. Data of patients, who were administered the first-line H. pylori eradication regimen at Tokyo Medical...
متن کاملEsophageal Eosinophilia Treated With Long-Duration Proton Pump Inhibitor Therapy
We present a case of proton pump inhibitor-responsive eosinophilic esophagitis (PPI-REE) in a patient with severe dysphagia and markedly elevated baseline esophageal eosinophilia that was previously deemed unresponsive to PPI. Upon reintroduction to PPI therapy with monthly endoscopy and dilation over the course of 4 months, the patient improved clinically and resolved her mucosal eosinophilia....
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ژورنال
عنوان ژورنال: Canadian Journal of Gastroenterology
سال: 2008
ISSN: 0835-7900
DOI: 10.1155/2008/284165